Cutaneous Drug Eruptions

Learning Objectives:

• Define cutaneous drug eruptions (CADRs): Be able to describe what cutaneous drug eruptions are and their general characteristics.
• Identify the spectrum of CADR manifestations: Understand that CADRs can present in various ways, from mild rashes to severe and life-threatening conditions.
• Explain the pathophysiology: Describe the underlying mechanisms (e.g., immune-mediated) that cause drug-related skin reactions.
• Recognize common types of CADRs: Be able to identify and describe the clinical features of specific CADRs, such as:
  • Exanthematous (morbilliform) eruptions
  • Acute generalized exanthematous pustulosis (AGEP)
  • Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN)
• List common causative drugs: Identify drugs frequently associated with SJS and TEN.
• Discuss the importance of medication history: Understand the critical role of obtaining a detailed history of all medications, including onset, duration, and dosage.
• Recognize the challenges in diagnosis: Be aware that diagnosing CADRs can be complex, especially in patients taking multiple medications.
• Understand the role of genetics: Recognize that certain genetic factors (e.g., HLA types) can increase the risk of specific drug reactions. 

Accreditation Statement for DOCME programs:

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the American Osteopathic Association (AOA). The Mississippi Osteopathic Medical Association (MOMA) is accredited by the American Osteopathic Association (AOA) to provide osteopathic continuing medical education for physicians.

Disclosure:  

Dr. David Roy has no actual or potential conflict of interest in relation to this program or presentation. 

Grievance Statement:

All grievances may be directed to MOMA's Executive Director at info@moma-net.org. All grievances will receive an initial response within 30 days of receipt.  If the participant does not receive a satisfactory response, they can submit a complaint to the Bureau of Osteopathic Education of the AOA at 142 East Ontario Street, Chicago, IL 60611